Two lions, two tigers and a Jaguar have escaped from a zoo in Lünebach in the western part of Germany, police have said.
Local authorities advised residents to stay inside their homes and call the police if they saw any of the five predators at large.
A bear had also escaped from the privately owned Eifel zoo, but was shot, a spokesperson told AFP.
German media report the animals were able to break out after flooding from a storm overnight.
The zoo, which was established in 1965 with only dogs, donkeys and a wild boar, is home to nearly 400 animals and is visited by 70,000 people a year, its website says.
It was not clear how the animals escaped nor exactly when they got out.