Earlier this year, the MLB stated they were keen for London to host its first regular-season game in 2017 but negotiations stalled before a deal could be agreed ,reports Reuters.
“Commissioner Manfred and the Mayor of London had a very good meeting on a variety of topics,” an MLB spokesperson told BBC Sport.
“Nothing specific has been determined regarding when a game might occur in London and what teams would participate.”
Khan, who threw the first pitch in the game between the New York Mets and Minnesota Twins last week, said the MLB were eager to tap into the European market.
“We’re in discussions about MLB and we want MLB to come to London,” he told reporters on Wednesday.
“What we’re discussing with Major League Baseball is for them to come here during the summer, which works for us for obvious reasons. They are very excited.”
The MLB could follow the lead of the National Football Association (NFL) and the National Basketball Association (NBA) if any deal is struck.